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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saladin, Darlin | SP | Peoria Chiefs | 22 | 12/28/2002 | San Pedro de Macorís | DOM | Right | Right | 5' 11" | 150 lbs | - |
| Salas, Ethan | C | Jersey Shore BlueClaws | 19 | 06/01/2006 | Kissimmee | USA | Left | Right | 6' 0" | 185 lbs | - |
| Salas, Jose | LF | Rome Braves | 22 | 04/26/2003 | Kissimmee | USA | Switch | Right | 6' 2" | 180 lbs | - |
| Salazar, Eduardo | SP | Greensboro Grasshoppers | 27 | 05/05/1998 | Cumana | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Salinas, Royber | CL | Fort Wayne TinCaps | 24 | 04/10/2001 | Guarenas | VEN | Right | Right | 6' 3" | 205 lbs | $760,000 |
| Samaniego, Tyler | RP | Brooklyn Cyclones | 26 | 01/30/1999 | Huntsville | USA | Right | Left | 6' 4" | 205 lbs | - |
| Sanchez, Axel | SS | Eugene Emeralds | 22 | 12/10/2002 | Santo Domingo | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sanchez, Carlos | C | Brooklyn Cyclones | 20 | 01/12/2005 | Valencia | VEN | Switch | Right | 5' 9" | 175 lbs | - |
| Sanchez, Yohendry | C | Winston-Salem Dash | 18 | 11/09/2006 | Valencia | VEN | Right | Right | 5' 11" | 200 lbs | - |
| Sanders, Will | SP | South Bend Cubs | 23 | 03/30/2002 | Atlanta | USA | Left | Right | 6' 6" | 230 lbs | - |
| Sanford, Wyatt | 2B | Asheville Tourists | 19 | 11/24/2005 | Frisco | USA | Left | Right | 6' 1" | 175 lbs | - |
| Santana, Natanael | CF | Free Agent | 24 | 07/27/2001 | Maimón | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Santana2, Cristian | 3B | Beloit Sky Carp | 21 | 11/25/2003 | Azua | DOM | Right | Right | 5' 11" | 165 lbs | - |
| Santos, Winston | SP | Cedar Rapids Kernels | 23 | 04/15/2002 | Unknown | DOM | Right | Right | 6' 0" | 160 lbs | - |
| Santucci, Jonathan | SP | Winston-Salem Dash | 22 | 12/28/2002 | Leominster | USA | Left | Left | 6' 2" | 205 lbs | - |
| Saucke II, Casey | RF | Everett AquaSox | 22 | 07/24/2003 | Rochester | USA | Right | Right | 6' 3" | 210 lbs | - |
| Schaeffer, Brandon | RP | Greenville Drive | 26 | 06/05/1999 | Unknown | USA | Left | Left | 6' 2" | 195 lbs | - |
| Schnell, Nick | RF | Bowling Green Hot Rods | 25 | 03/27/2000 | Indianapolis | USA | Left | Right | 6' 1" | 180 lbs | - |
| Schweitzer, Tyler | SP | Spokane Indians | 25 | 09/19/2000 | Fishers | USA | Left | Left | 6' 0" | 185 lbs | - |
| Sears, Brett | SP | Cedar Rapids Kernels | 25 | 05/02/2000 | Harlan | USA | Right | Right | 6' 1" | 200 lbs | - |
| Seminaris, Adam | SP | Tri-City Dust Devils | 27 | 10/19/1998 | Chino Hills | USA | Right | Left | 6' 0" | 190 lbs | - |
| Sequera, Manuel | 2B | Great Lakes Loons | 23 | 09/28/2002 | Barquisimeto | VEN | Right | Right | 6' 1" | 170 lbs | - |
| Serrano, Elio | RP | Free Agent | 27 | 08/02/1998 | Valencia | VEN | Right | Right | 5' 11" | 160 lbs | - |
| Servideo, Anthony | SS | Fort Wayne TinCaps | 26 | 03/11/1999 | Jupiter | USA | Left | Right | 5' 11" | 170 lbs | - |
| Shields, David | SP | West Michigan Whitecaps | 19 | 09/09/2006 | Pittsburgh | USA | Switch | Left | 6' 2" | 210 lbs | - |
| Shliger, Luke | C | Cedar Rapids Kernels | 24 | 09/25/2001 | Danbury | USA | Left | Right | 5' 9" | 180 lbs | - |
| Sikes, Phillip | CF | Hillsboro Hops | 26 | 04/27/1999 | Paris | USA | Right | Right | 6' 2" | 190 lbs | - |
| Silva, Eric | CL | Hudson Valley Renegades | 23 | 10/03/2002 | Laguna Beach | USA | Right | Right | 6' 1" | 185 lbs | - |
| Simas, Kohl | SP | Lake County Captains | 25 | 12/22/1999 | Fresno | USA | Right | Right | 6' 1" | 190 lbs | - |
| Simon, Liam | SP | Hudson Valley Renegades | 25 | 10/16/2000 | Princeton | USA | Right | Right | 6' 4" | 220 lbs | - |
| Simpson, Will | 3B | Brooklyn Cyclones | 24 | 08/28/2001 | Sammamish | USA | Right | Right | 6' 3" | 225 lbs | - |
| Sirota, Mike | LF | West Michigan Whitecaps | 22 | 06/16/2003 | New York | USA | Right | Right | 6' 2" | 175 lbs | - |
| Sisneros, Cameron | 1B | Fort Wayne TinCaps | 24 | 06/01/2001 | Littleton | USA | Left | Left | 6' 2" | 230 lbs | - |
| Skipper, Carson | RP | Spokane Indians | 26 | 08/12/1999 | Trussville | USA | Left | Left | 6' 2" | 210 lbs | - |
| Smith, Austin | CL | Lake County Captains | 26 | 06/22/1999 | Cedar Park | USA | Right | Right | 6' 4" | 210 lbs | - |
| Smith, Caswell | SP | Aberdeen Ironbirds | 24 | 01/26/2001 | Jasper | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, D'Andre | 2B | Cedar Rapids Kernels | 24 | 05/10/2001 | Diamond Bar | USA | Right | Right | 5' 9" | 180 lbs | - |
| Smith, Marcus | CF | Wisconsin Timber Rattlers | 25 | 09/11/2000 | Kansas City | USA | Left | Left | 5' 11" | 190 lbs | - |
| Smith, Tristan | SP | Eugene Emeralds | 22 | 05/25/2003 | Chesnee | USA | Right | Left | 6' 2" | 200 lbs | - |
| Soler, Yassel | 3B | Quad Cities River Bandits | 19 | 01/26/2006 | Santo Domingo | DOM | Right | Right | 5' 11" | 185 lbs | - |
| Soriano, George | RP | Free Agent | 26 | 03/24/1999 | San Pedro de Macorís | DOM | Right | Right | 6' 2" | 210 lbs | - |
| Soto, Charlee | SP | Greensboro Grasshoppers | 20 | 08/31/2005 | Kissimmee | USA | Switch | Right | 6' 5" | 210 lbs | - |
| Spain, Garrett | RF | Everett AquaSox | 25 | 09/21/2000 | Clarksville | USA | Left | Right | 5' 11" | 180 lbs | - |
| Sparks, Lamar | RF | Greensboro Grasshoppers | 27 | 09/26/1998 | Katy | USA | Right | Right | 6' 2" | 170 lbs | - |
| Spiers, Carson | SP | Free Agent | 27 | 11/11/1997 | Greenville | USA | Right | Right | 6' 3" | 205 lbs | - |
| Spohn, Harrison | 2B | Free Agent | 26 | 12/03/1998 | Upland | USA | Right | Right | 6' 1" | 200 lbs | - |
| Squires, Brett | 1B | Cedar Rapids Kernels | 25 | 02/26/2000 | Grapevine | USA | Left | Right | 6' 3" | 210 lbs | - |
| Stafura, Sammy | 2B | Asheville Tourists | 20 | 11/15/2004 | Lake Mohegan | USA | Right | Right | 6' 0" | 185 lbs | - |
| Staine, Connor | RP | Hickory Crawdads | 24 | 01/12/2001 | Clinton | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stehly, Murphy | 3B | Brooklyn Cyclones | 27 | 09/27/1998 | Carlsbad | USA | Right | Right | 5' 10" | 205 lbs | - |
| Steinbaugh, Conor | RP | South Bend Cubs | 26 | 05/22/1999 | Akron | USA | Right | Right | 6' 0" | 205 lbs | - |
| Steinmetz, Jacob | SP | Greensboro Grasshoppers | 22 | 07/19/2003 | Woodmere | USA | Right | Right | 6' 6" | 230 lbs | - |
| Stephenson, Seth | CF | Brooklyn Cyclones | 24 | 01/10/2001 | Buda | USA | Switch | Right | 5' 9" | 165 lbs | - |
| Stevens, Felix | LF | Lansing Lugnuts | 26 | 07/30/1999 | Havana | CUB | Right | Right | 6' 4" | 235 lbs | - |
| Stewart, DJ | LF | Tri-City Dust Devils | 31 | 11/30/1993 | Gainesville | USA | Left | Right | 6' 0" | 210 lbs | - |
| Stewart, Joe | CF | Free Agent | 27 | 05/06/1998 | Portage | USA | Right | Right | 6' 4" | 195 lbs | - |
| Sthele, Travis | SP | Aberdeen Ironbirds | 24 | 09/21/2001 | San Antonio | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stovall, Peyton | 2B | Wisconsin Timber Rattlers | 22 | 02/14/2003 | Haughton | USA | Left | Right | 6' 0" | 185 lbs | - |
| Strickland, Samuel | RP | Great Lakes Loons | 26 | 03/26/1999 | Birmingham | USA | Right | Left | 6' 2" | 220 lbs | - |
| Strowd, Kade | RP | Everett AquaSox | 28 | 09/17/1997 | Ft. Worth | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sugastey, Adrian | C | Lansing Lugnuts | 23 | 10/23/2002 | Porlamar | VEN | Right | Right | 6' 1" | 210 lbs | - |
| Sullivan, Billy | RP | Free Agent | 26 | 04/16/1999 | Wilmington | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sullivan, Brett | LF | Free Agent | 31 | 02/22/1994 | Stockton | USA | Left | Right | 5' 10" | 195 lbs | - |
| Sullivan, Joseph | 1B | Quad Cities River Bandits | 23 | 07/01/2002 | Birmingham | USA | Left | Left | 5' 11" | 200 lbs | - |
| Sullivan2, Sean | SP | Greenville Drive | 23 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
| Svanson, Matt | RP | Spokane Indians | 26 | 01/31/1999 | Hawthorn Woods | USA | Right | Right | 6' 5" | 235 lbs | - |
