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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Hearn, Ryan | 1B | Cincinnati Reds | 32 | 07/26/1993 | Frisco | USA | Left | Left | 6' 3" | 220 lbs | $2,400,000 |
| O'Hoppe, Logan | C | Oakland Athletics | 25 | 02/09/2000 | Birmingham | USA | Right | Right | 6' 2" | 185 lbs | $760,000 |
| O'Neill, Tyler | LF | Atlanta Braves | 30 | 06/22/1995 | Vancouver | CAN | Right | Right | 5' 11" | 200 lbs | $7,500,000 |
| Ober, Bailey | SP | Atlanta Braves | 30 | 07/12/1995 | Huntersville | USA | Right | Right | 6' 9" | 260 lbs | $1,749,000 |
| Ocasio, Esteban | CF | Free Agent | 16 | 03/12/2009 | Salinas | USA | Right | Right | 6' 4" | 180 lbs | - |
| October, Luis | C | Free Agent | 22 | 03/06/2003 | Delano | USA | Right | Right | 6' 4" | 195 lbs | - |
| Oduro, Donte | SP | Free Agent | 21 | 07/08/2004 | Sedalia | USA | Right | Right | 6' 0" | 175 lbs | - |
| Ofori, Treshaun | SP | Free Agent | 20 | 03/03/2005 | Hampton | USA | Right | Right | 5' 11" | 170 lbs | - |
| Ogando, Gerald | RP | Free Agent | 25 | 07/28/2000 | Santo Domingo | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Ogans, Keshawn | 2B | Free Agent | 24 | 08/26/2001 | San Francisco | USA | Right | Right | 5' 8" | 180 lbs | - |
| Ogarro, Tyrese | RF | Free Agent | 19 | 11/07/2005 | New Boston | USA | Left | Left | 6' 4" | 185 lbs | - |
| Ohtani, Shohei | SP | Colorado Rockies | 31 | 07/05/1994 | Iwate | JPN | Left | Right | 6' 4" | 210 lbs | $6,000,000 |
| Ojeda Jr., Miguel | C | Free Agent | 25 | 06/16/2000 | Guaymas | MEX | Switch | Right | 6' 0" | 160 lbs | - |
| Ojo, Jose | RP | Free Agent | 24 | 05/17/2001 | Panama | PAN | Right | Right | 6' 0" | 170 lbs | - |
| Olguin, Fernando | SP | Free Agent | 24 | 03/04/2001 | Tijuana | MEX | Right | Right | 5' 9" | 155 lbs | - |
| Oliver, Connor | SP | Free Agent | 24 | 06/29/2001 | Chicago | USA | Left | Left | 6' 2" | 170 lbs | - |
| Olson, Matt | 1B | Chicago White Sox | 31 | 03/29/1994 | Atlanta | USA | Left | Right | 6' 5" | 225 lbs | $37,500,000 |
| Olson, Reese | RP | Detroit Tigers | 26 | 07/31/1999 | Lula | USA | Right | Right | 6' 1" | 160 lbs | $760,000 |
| Omlid, Hunter | SP | Free Agent | 26 | 08/31/1999 | Hamilton | USA | Right | Right | 6' 2" | 200 lbs | - |
| Omori, Goh | SP | Free Agent | 18 | 10/24/2007 | Yachimata | JPN | Right | Right | 6' 4" | 180 lbs | - |
| Ongeri, Mutara | SP | Free Agent | 18 | 01/04/2007 | Los Angeles | USA | Right | Left | 6' 4" | 175 lbs | - |
| Onuoha, Gerain | SP | Free Agent | 18 | 01/28/2007 | Pleasantville | USA | Left | Left | 6' 6" | 185 lbs | - |
| Onuoha, Raheem | RF | Free Agent | 22 | 09/22/2003 | Ontario | USA | Right | Right | 6' 0" | 180 lbs | - |
| Oquendo, Johzan | RP | Free Agent | 24 | 01/06/2001 | Carolina | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Orellana, Luis | SP | Free Agent | 18 | 04/28/2007 | San Jose | USA | Left | Left | 6' 5" | 185 lbs | - |
| Ornelas, Juan | SP | Free Agent | 22 | 04/12/2003 | St. Marys | USA | Left | Left | 6' 2" | 185 lbs | - |
| Ornelas, Luis | SP | Free Agent | 18 | 08/20/2007 | Santa Ana | USA | Left | Right | 6' 6" | 195 lbs | - |
| Orozco, Alfredo | SP | Free Agent | 22 | 04/08/2003 | Las Vegas | USA | Left | Right | 6' 8" | 215 lbs | - |
| Orozco, Jorge | SP | Free Agent | 20 | 05/23/2005 | Riverside | USA | Left | Right | 6' 5" | 200 lbs | - |
| Orozco, Juan | CF | Free Agent | 22 | 09/07/2003 | Houston | USA | Right | Right | 6' 0" | 175 lbs | - |
| Ortega, Ernesto | 2B | Free Agent | 17 | 01/05/2008 | Pittsburgh | USA | Right | Right | 6' 2" | 160 lbs | - |
| Ortega, Fernando | SP | Free Agent | 24 | 10/10/2001 | Santiago | DOM | Right | Right | 6' 4" | 160 lbs | - |
| Ortega, Jesus | CF | Free Agent | 24 | 01/18/2001 | Valencia | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Ortega, Rafael | CF | Boston Red Sox | 34 | 05/15/1991 | El Tigre | VEN | Left | Right | 5' 11" | 200 lbs | $2,400,000 |
| Ortega, Sergio | RP | Free Agent | 18 | 01/06/2007 | Santo Domingo | DOM | Switch | Right | 5' 9" | 145 lbs | - |
| Ortega, Wilmer | RP | Free Agent | 24 | 04/04/2001 | San Felipe | VEN | Right | Right | 6' 1" | 170 lbs | - |
| Ortiz, Francisco | C | Free Agent | 26 | 09/15/1999 | Caracas | VEN | Right | Right | 6' 0" | 160 lbs | - |
| Ortiz, Joey | SS | Seattle Mariners | 27 | 07/14/1998 | Garden Grove | USA | Right | Right | 5' 11" | 175 lbs | $760,000 |
| Ortiz, Luis | SP | Baltimore Orioles | 26 | 01/27/1999 | San Pedro de Macorís | DOM | Right | Right | 6' 2" | 235 lbs | $12,000,000 |
| Osagie, Omari | CF | Free Agent | 17 | 02/28/2008 | New York | USA | Left | Left | 6' 0" | 160 lbs | - |
| Osman, Graham | SP | Free Agent | 24 | 01/29/2001 | Unknown | USA | Left | Left | 6' 3" | 185 lbs | - |
| Otanez, Michel | RP | Philadelphia Phillies | 28 | 07/03/1997 | La Mata | DOM | Right | Right | 6' 4" | 235 lbs | $1,500,000 |
| Otero, Andy | SP | Free Agent | 33 | 06/03/1992 | David | PAN | Left | Left | 5' 9" | 160 lbs | - |
| Ottavino, Adam | RP | Baltimore Orioles | 39 | 11/22/1985 | New York | USA | Switch | Right | 6' 5" | 240 lbs | $760,000 |
| Ouderkirk, Daniel | SP | Free Agent | 25 | 03/16/2000 | Unknown | USA | Right | Right | 6' 9" | 255 lbs | - |
| Outley, Rashan | RP | Free Agent | 21 | 09/03/2004 | Cameron | USA | Right | Right | 6' 2" | 195 lbs | - |
| Outman, James | RF | Texas Rangers | 28 | 05/14/1997 | Redwood City | USA | Left | Right | 6' 3" | 215 lbs | $760,000 |
| Ovando, Anyelo | RP | Free Agent | 24 | 12/25/2000 | San Pedro de Macorís | DOM | Right | Right | 6' 5" | 225 lbs | - |
| Overton, Connor | SP | Free Agent | 32 | 07/24/1993 | Mechanicsville | USA | Left | Right | 6' 0" | 190 lbs | - |
| Oviedo, Johan | SP | Milwaukee Brewers | 27 | 03/02/1998 | Havana | CUB | Right | Right | 6' 5" | 210 lbs | $1,560,000 |
| Owusu, Zion | SP | Free Agent | 21 | 02/03/2004 | Chowchilla | USA | Right | Right | 6' 7" | 205 lbs | - |
| Ozuna, Marcell | RF | New York Yankees | 34 | 11/12/1990 | Santo Domingo | DOM | Right | Right | 6' 1" | 225 lbs | $6,700,000 |
